Pluto Bioinformatics

GSE119241: Differential gene expression analysis in BRD4-PROTAC treated diffuse large B-cell lymphoma cell lines

Bulk RNA sequencing

We identified differential gene expression after treatment with BRD4-PROTAC ARV771 in two ABC-like diffuse large B-cella lymphoma cell lines. We have identified cluster of gene expression regulated after BRD4 inhibition which are criticaly important for DLBCL malignancy. SOURCE: Michael Green (MGreen5@mdanderson.org) - MD Anderson Cancer Center