Pluto Bioinformatics

GSE108658: EGFR-targeted therapy-induced resistance mechanism in glioblastoma

Bulk RNA sequencing

Analysis of mouse glioma tumors (in RAG1-/- mouse host) overexpressing Control(C) or Slug(S) viruses, and treated with doxycyclin(D) to turn off EGFRviii expression. Results provide insight into molecular basis of EGFRviii targeted therapy-induced resistence in GBM. SOURCE: Jihye Paik (Jep2025@med.cornell.edu) - Weill Cornell Medical College