Pluto Bioinformatics

GSE109074: Gene expression in adult sciatic nerves upon miRNA ablation and crush injury

Bulk RNA sequencing

We report RNA sequencing data from induced Schwann cell specific knockouts for DICER and DGCR8 as well as crush injured wild type animals. Induced deletion of DICER and DGCR8 results in expression of numerous injury response genes suggesting a requirement of those proteins in maintaining the myelinated Schwann cell fate. SOURCE: Ueli Suter (usuter@cell.biol.ethz.ch) - Suter ETH Zurich