Pluto Bioinformatics

GSE108526: IRF5 and IRF3 regulate distinct immune programs in plasmacytoid dendritic cells

Bulk RNA sequencing

Transcriptomic analyses of pDCs show that the partitioning of TLR/IRF5 and RLR/IRF3 pathways confers differential gene expression and immune cytokine production in pDCs, linking IRF5 with immune regulatory and proinflammatory gene expression. SOURCE: Michael Gale, Jr (data@ciiid.washington.edu) - University of Washington