Pluto Bioinformatics

GSE115403: Inflammation-produced TNF protects hematopoietic stem cells from necroptosis and promotes hematopoietic regeneration

Bulk RNA sequencing

To gain molecular insights into the differential effect of TNF between hematopoietic stem cells (HSC) and downstream myeloid progenitors, we performed RNA-sequencing analyses of HSCs and granulocyte-macrophage progenitors (GMP) treated with TNF both ex vivo and in vivo. SOURCE: Masayuki Yamashita Institute of Medical Science, University of Tokyo