Pluto Bioinformatics

GSE96093: RNA-sequencing of hepatocyte specific ABCA1 deletion mice

Bulk RNA sequencing

ATP binding cassette transporter A1 (ABCA1) regulates cellular cholesterol efflux. We characterized the gene expression changes following hepatocyte specific ABCA1 deletion in mice. We report that genes and pathways related to lipogenesis were downregulated in mice with hepatocyte specific ABCA1 deletion compared to floxed controls. SOURCE: Praveen Sethupathy UNC