Pluto Bioinformatics

GSE152460: RNA-seq of ATF-3 overexpressing and Neomycin control melanoma cell lines

Bulk RNA sequencing

The present study demonstrates that ATF-3 plays a tumor suppressing function in melanoma. Overexpression of ATF-3 in metastatic melanoma cell lines significantly inhibited their growth, migration and invasion in vitro as well as inhibited tumor growth in human melanoma xenograft mouse model in vivo. SOURCE: Natasha FrankNatasha Frank Brigham and Women's Hospital