We generated the cardiac-specific knockout of Trbp (Trbp-cKO) in mice. We profiled the transcriptome in both wild-type and Trbp-cKO hearts, and found numerous genes were deregulated by deletion of Trbp. We also profiled miRNA expression both wild-type and Trbp-cKO hearts, and found expression of a subset of miRNA species was altered in Trbp-cKO hearts. SOURCE: Da-Zhi Wang (dwang@enders.tch.harvard.edu) -  Boston Children's Hospital

Pluto Bioinformatics

GSE67658: Effects of Trbp deletion on gene expession in mice hearts