Pluto Bioinformatics

GSE108406: MDM2 inhibitors reverse the transcriptional effects of DMKG plus B87.

Bulk RNA sequencing

We reported for the first time that DMKG plus B87 kills cancer cells through a MDM2-dependent cell death mechanism (unpublished results). Moreover, we demonstrated that this effect is reverted by MDM2 inhibitors. We investigated if this effect is transcriptional. SOURCE: Pierre de la Grange ( - GenoSplice technology

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