Pluto Bioinformatics

GSE108406: MDM2 inhibitors reverse the transcriptional effects of DMKG plus B87.

Bulk RNA sequencing

We reported for the first time that DMKG plus B87 kills cancer cells through a MDM2-dependent cell death mechanism (unpublished results). Moreover, we demonstrated that this effect is reverted by MDM2 inhibitors. We investigated if this effect is transcriptional. SOURCE: Pierre de la Grange (pierre.delagrange@genosplice.com) - GenoSplice technology