Pluto Bioinformatics

GSE149348: Wnt Signaling Mediates Oncogenic Synergy Between Akt and Dlx5 in T-Cell Lymphomagenesis by Enhancing Cholesterol Synthesis [mouse PKF RNA-seq]

Bulk RNA sequencing

Akt2;Dlx5 double transgenic mice develops T-ALL, and these cells have up regulated Cholesterol synthesis via Wnt pathway for survival SOURCE: yinfei tan (Yinfei.Tan@fccc.edu) - NGS-research Fox Chase Cancer Center