Pluto Bioinformatics

GSE73541: Neutrophils oppose uterine epithelial carcinogenesis via debridement of hypoxic tumor cells

Bulk RNA sequencing

Our study demonstrates that neutrophils infiltrate early-stage PTEN-deficient uterine tumors and oppose tumor growth and malignant progression by inducing detachment and ultimately promoting cell death of tumor cells.; This RNA-seq study examined the expression profiles of these uterine epithelial tumor cells in the presence versus absence of neutrophil infiltration. SOURCE: Adam Blaisdell (adam.blaisdell@nyumc.org) - NYU School of Medicine