Pluto Bioinformatics

GSE156612: Stem cell-derived neutrophil-primed progenitors prevent lethal infection

Bulk RNA sequencing

We show that engineered neutrophil-primed progenitors derived from human induced pluripotent stem cells (NeuPs-XL) can produce functional neutrophil-like cells (NeuCs-XL) that can act promptly in vivo against lethal bacterial infections at a clinically applicable scale. We performed global gene expression profiling of NeuPs-XL and NeuCs-XL with or without LPS stimulation. SOURCE: Yusuke Ito (yuusuitou-tky@umin.ac.jp) - The University of Tokyo