Pluto Bioinformatics

GSE148205: Memory like NK cells display stem cell like properties after Zika virus Infection

Bulk RNA sequencing

Here we show that Zika virus infection induces memory like NK cells that express CD27. This subset shared transcriptional changes with memory CD8 T cells, stem cells and stem like T cells. These NK cells with memory and stemness features which we term NK memory stem cells (SCMNK) demonstrated greater antiviral potential. Transcriptional data of SCMNK and non-memory NK cells is presented. SOURCE: Sachin Mulik (sachin.mulik@uthct.edu) - The University of Texas Health Science Center at Tyler