Pluto Bioinformatics

GSE41658: Methylomic analysis identifies the involvement of migration and adhesion genes in the ageing of primary haematopoietic stem cells

Bulk RNA sequencing

we utilize Nano-MeDIP-seq for the analysis of the LT-HSC methylome and, for the first time, simultaneously interrogate the methylome and transcriptome of a homogeneous population of primary murine HSCs, in order to define the underlying causes of changes in HSC functionality during normal ageing. SOURCE: Gareth Wilson (gareth.wilson@ucl.ac.uk) - UCL Cancer Institute