Pluto Bioinformatics

GSE108330: Next Generation Sequencing Facilitates Quantitative Analysis of mRNA lifetime of Wild Type and Mettl3-/- mice

Bulk RNA sequencing

Considering m6A modification in mRNA was reported to be intensively correlated with RNA decay, for example, T cells and neurone cells. We wondered whether deleting Mettl3, the main catalzing enzyme, affect the RNA stability of mouse dendritic cells. SOURCE: Huamin Wang (huamin_wang86@163.com) - Peking Union Medical College, Chinese Academy of Medical Sciences,