Pluto Bioinformatics

GSE72964: Tissue damage signals repurpose NF-B, AP-1 and Smad3 to direct a Rev-erb sensitive wound healing program in macrophages

Bulk RNA sequencing

A complex damage signal promotes co-localization of NFB and Smad3 at Rev-erb-sensitive enhancers and drives expression of genes characteristic of alternate polarization states in the same cells. SOURCE: Christopher Glass (ckg@ucsd.edu) - Glass Lab University of California, San Diego