Pluto Bioinformatics

GSE148263: The ubiquitin ligase TRIM37 controls cancer-specific vulnerability to PLK4 inhibition

Bulk RNA sequencing

We show synthetic lethality between PLK4 inhibition-mediated centrosome loss and the overexpression of the ubiquitin ligase TRIM37 in cancer cells with amplification of Chr17q SOURCE: Karen Oegema ( - UCSD

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