Pluto Bioinformatics
GSE142204: Effect of RAGE on macrophage transcriptome in regression of diabetic atherosclerosis
Bulk RNA sequencing
Ldlr null (Ager+/+ Ldlr-/-) diabetic mice were raised on a Western diet.; Their aortas were transplanted to diabetic mice rasied on standard chow,; which were either WT (Ager+/+ Ldlr+/+) or Ager null (Ager-/- Ldlr+/+). The; gene expression profile of either the donor (CD45.2) or recipient (CD45.1); sorted macrophages from both genotypes was studied. SOURCE: Richard,A,FriedmanCancer Center Columbia University Irving Medical Center