Pluto Bioinformatics

GSE139647: "TRADES": Targeted RNA demethylation by Suntag system

Bulk RNA sequencing

We engineered a new m6A editing system consisting of GCN4 (SunTag)-dCas13b, anti-GCN4 single chain variable fragment (scFv)-FTO or ALKBH5-GBI and sgRNA to provide an applicable method to remove m6A modification at specific loci. SOURCE: Zonggui Chen (chenzonggui@whu.edu.cn) - YuZhou Wuhan University