Pluto Bioinformatics

GSE148222: Next Generation Sequencing of expression profile from synchronized WT and BRD4 KO MEFs cells at different time point

Bulk RNA sequencing

Brd4f/f ERT2Cre MEFs are a type of fibroblast prepared from Brd4f/f ERT2Cre/- mouse embryo. MEFs are widely used in life science researches, especially in stem cell biology. Using RNAseq it was shown that many of cell cycle genes were under control of BRD4. Purpose of this study was to assess the effect of BRD4 KO in NGS derived transcriptome profiles of both WT and BRD4KO cells. SOURCE: Jack Chen NIH