Pluto Bioinformatics

GSE142871: PIM kinase inhibition in HCC xenograft

Bulk RNA sequencing

Human HCC cell line, MHCC-97L, was subcutaneously injected to BALB/c nude mice. Two weeks post injection, mice were randomised to receive vehicle or PIM447 (60mg/kg) by oral gavage three times a week for two weeks. Total RNA was extracted from the tumor xenograft (Vehicle, n=2; PIM447, n=2) and subjected to RNA sequencing. Expression profiling of the tumors between vehicle control and PIM447 treated groups was compared. SOURCE: Chi Ho Lin (nicklin.cpos@hku.hk) - The University of Hong Kong