Pluto Bioinformatics

GSE62909: SOX15 governs a transcriptional program in human esophageal stratified epithelium and in a subset of esophageal adenocarcinomas

Bulk RNA sequencing

We identified spatially restricted transcription factors and found SOX15 expression confined to stratified esophageal epithelium, with attenuation in Barrett's esophagus.; SOX15 binds esophagus-specific loci and its loss in human esophageal cells affected esophagus-specific transcripts SOURCE: Ramesh,Arjun,Shivdasani (Ramesh_Shivdasani@dfci.harvard.edu) - Shivdasani Dana Farber Cancer Institute

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