Pluto Bioinformatics

GSE117547: Crebbp loss drives small cell lung cancer and increases sensitivity to HDAC inhibition[SCLC]

Bulk RNA sequencing

This study assessed tumor suppressor roles of CREBBP in SCLC and other neuroendocrine tumors. Genetically engineered mouse models were used to determine the tumor suppressor role of Crebbp in SCLC and other neuroendocrine tumors. SOURCE: David MacPherson Fred Hutchinson Cancer Research Center