Pluto Bioinformatics

GSE116637: RNA-seq of eight lymphoblastoid cell lines after AHR ligand treatments

Bulk RNA sequencing

RNA-seq was done on eight different lymphoblastoid cell lines for vehicle control, 3-MC agonist treatment and GNF-351 antagonist treatment for AHR to look at AHR regulated genes with different genetic backgrounds. We identified 69 genes that were highly differentially expressed after 3-MC or GNF-351 antagonist treatment with variation in the degree fo differential expression between the eight cell lines. SOURCE: Richard Weinshilboum (Weinshilboum.Richard@mayo.edu) - Mayo Clinic