Pluto Bioinformatics

GSE107980: RING-finger protein 6 amplification activates JAK/STAT3 pathway by modifying SHP-1 ubiquitylation and associates with poor outcome in colorectal cancer

Bulk RNA sequencing

To elucidate whether RNF6 plays a role in colorectal cancer tumorigenesis, a RNA-seq analysis was performed to compare the gene expression profiles of RNF6 siRNA and control siRNA transfectants. SOURCE: Haoyan Chen (haoyanchen@shsmu.edu.cn) - Renji Hospital